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PMID: 301 XiaoH-HMokD-WYaoX-SWongM-S

However, mutant variants such as A53T bind to the lysosomal receptor LAMP2A but fail to translocate into the lumen, resulting in a blockage that impairs not only their own degradation but also that of other CMA substrates [171, 172]

Tsai SW, Tung YT, Chen HL, Yang SH, Liu CY, Lu M, Pai HJ, Lin CC, Chen CM (2016) Myostatin propeptide gene delivery by gene gun ameliorates muscle atrophy in a rat model of botulinum toxin-induced nerve denervation